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Le mГ©dicament a Г©galement Г©tГ© utilisГ© pour attГ©nuer la somnolence diurne prГ©existante associГ©e Г la maladie de Parkinson, mais aucune Г©tude n'a examinГ© son efficacitГ© chez les patients atteints de la maladie de Parkinson. Les formes en vente libre sont prises jusqu'Г quatre fois par jour, une dose initiale Г©tant prise le matin et des doses supplГ©mentaires Г intervalles rГ©guliers tout au long de la journГ©e. Il peut ГЄtre pris avant le coucher ou peut ГЄtre pris en conjonction avec un repas. Il est disponible sur commande auprГЁs de trafiquants de drogue d'AmГ©rique centrale et d'AmГ©rique du Sud dans des pays comme le BrГ©sil, le Mexique et le Venezuela. On pense Г©galement que l'acide aminГ© phГ©nylalanine contenu dans le supplГ©ment apporte une contribution supplГ©mentaire Г l'Г©veil et diminue la somnolence. Aux Г‰tats-Unis, le Modafinil n'est pas disponible sur ordonnance. Le modafinil est prescrit pour rГ©duire la somnolence chez les personnes qui ont besoin de rester Г©veillГ©es ou d'avoir plus d'Г©nergie, comme les personnes qui ont des quarts de travail qui les fatiguent pendant la journГ©e. Le modafinil a Г©tГ© utilisГ© comme hormone de croissance dans le traitement du dГ©ficit en hormone de croissance. Le modafinil est classГ© dans la mГЄme classe que les amphГ©tamines telles que l'Adderall et est une substance contrГґlГ©e de l'annexe IV aux Г‰tats-Unis. Le modafinil est disponible en comprimГ©s de 50 mg, 100 mg et 150 mg. Modiodal En tant que stimulant, il peut provoquer une augmentation de la pression artГ©rielle, du rythme cardiaque et de la respiration. Aucune Г©tude Г long terme n'est disponible, il est donc difficile de savoir combien de temps vous devez prendre ce mГ©dicament. Un stress mental ou physique modГ©rГ© ou sГ©vГЁre peut augmenter le risque de symptГґmes de stress tels que maux de tГЄte ou agitation. Il est structurellement liГ© aux amphГ©tamines, qui sont des drogues communГ©ment appelГ©es В« meth В». Le mГ©dicament est pris une fois par jour au coucher, gГ©nГ©ralement le soir ou tГґt le lendemain matin. La dose maximale recommandГ©e pour les enfants est de 0,3 mg/kg, soit 300 mg pour un adulte de 70 kg. La narcolepsie se caractГ©rise par une somnolence excessive, des habitudes de sommeil perturbГ©es et de frГ©quentes crises de sommeil nocturne. Г‰vitez les nourrissons et les enfants pendant le traitement par Modafinil. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. Il n'est pas recommandГ© aux personnes souffrant d'hypertension non contrГґlГ©e d'utiliser le modafinil. Certains mГ©dicaments, y compris Modafinil, peuvent provoquer ou aggraver ces affections. Il est souvent utilisГ© par les athlГЁtes comme complГ©ment de prГ©-entraГ®nement pour amГ©liorer l'Г©nergie, l'Г©veil et la vigilance. Le modafinil a Г©tГ© dГ©couvert pour stimuler la production de dopamine et de sГ©rotonine chez la souris. De rares rГ©actions dermatologiques graves peuvent survenir chez les personnes prГ©sentant des prГ©dispositions gГ©nГ©tiques et plus frГ©quemment chez les patients pГ©diatriques. Il amГ©liore l'Г©veil et l'activitГ© et peut provoquer une lГ©gГЁre euphorie.
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Sa demi-vie d'Г©limination est d'environ 3 Г 6 heures. Il a Г©tГ© dГ©crit pour augmenter l'Г©veil, amГ©liorant la vigilance et la concentration pendant la journГ©e. Des Г©tudes in vivo montrent que le mГ©dicament agit Г la fois comme un antagoniste des rГ©cepteurs A2A et comme un faible inhibiteur de la recapture de l'adГ©nosine. Le modafinil peut ГЄtre pris avec ou sans nourriture. Le modafinil est Г©galement parfois utilisГ© comme activateur cognitif, Г©galement connu sous le nom de nootropiques, pour amГ©liorer la productivitГ©. Le mГ©canisme d'action du modafinil est attribuГ© Г cette interaction de liaison entre le mГ©dicament actif et les protГ©ines du bulbe olfactif. Le modafinil est le plus souvent pris en une seule dose de 200 mg. Modafinil est un nom de marque pour le modafinil Г libГ©ration prolongГ©e, qui est la forme la plus couramment utilisГ©e du mГ©dicament. On ne sait pas si le modafinil est efficace pour les personnes atteintes de narcolepsie. Chez l'homme, le mГ©dicament a Г©tГ© Г©tudiГ© comme traitement potentiel de la maladie d'Alzheimer et de la maladie de Parkinson, mais les rГ©sultats ne sont actuellement pas concluants. Certaines personnes peuvent penser que 200 mg sont suffisants, tandis que d'autres peuvent avoir besoin de 300 mg ou mГЄme plus. Modiodal Il est important que le modafinil soit pris avant de dormir. Modafinil est un comprimГ© Г libГ©ration prolongГ©e (Г©lixible). Ce supplГ©ment est Г©galement disponible sous forme de gГ©lule molle. La formule du modafinil est ®-phГ©nylacГ©tylcarbinol + (S)-phГ©nylacГ©tylcarbinol, et le produit chimique principal est : 2-(benzhydrylsulfinyl)acГ©taldГ©hyde. Une Г©tude chez l'animal suggГЁre qu'il est capable d'amГ©liorer la mГ©moire et la rГ©tention Г long terme, et d'augmenter la survie de nouveaux neurones. Des concentrations de modafinil supГ©rieures Г 350 ng/ml indiquent que le mГ©dicament ne fonctionne pas. Ces effets peuvent provoquer chez certaines personnes une agitation ou des Г©tourdissements ou des Г©vanouissements. L'arrГЄt est recommandГ© dГЁs les premiers signes d'Г©ruption cutanГ©e ou de rГ©actions similaires. Le modafinil peut Г©galement causer des problГЁmes chez les enfants et son utilisation n'est pas recommandГ©e pendant la grossesse. Le modafinil est un stimulant du systГЁme nerveux central (SNC) avec une indication non indiquГ©e sur l'Г©tiquette potentielle pour amГ©liorer la fonction cognitive chez les personnes souffrant de privation de sommeil Г la suite d'un travail postГ©, ou comme traitement d'appoint pour les personnes souffrant de troubles caractГ©risГ©s par une somnolence diurne excessive, comme narcolepsie et apnГ©e obstructive du sommeil. Le modafinil se lie aux rГ©cepteurs de la dopamine, mais seulement dans une certaine mesure. On pense que le mГ©dicament amГ©liore l'Г©veil du systГЁme nerveux central et a Г©tГ© utilisГ© avec succГЁs pour le traitement de la somnolence excessive chez les patients narcoleptiques. Le modafinil est destinГ© Г ГЄtre utilisГ© comme agent d'Г©veil, l'utilisation la plus courante Г©tant le traitement de la somnolence due au travail postГ©.
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12-04-2022, 10:57 AM
(This post was last modified: 12-04-2022, 11:00 AM by BrandonUttet.)
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12-04-2022, 11:01 AM
(This post was last modified: 12-04-2022, 11:02 AM by BrandonUttet.)
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