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01-03-2023, 11:18 PM
(This post was last modified: 01-03-2023, 11:19 PM by Modafinil 200.)
Il a d'abord Г©tГ© brevetГ© en tant que 1-(benzhydrylsulfinyl) indole. Certaines personnes peuvent Г©galement ressentir une diminution de l'appГ©tit, une diminution de la libido et de la fatigue. Le modafinil est un petit composГ© organique qui est un analogue direct de l'amphГ©tamine. Initialement, Modafinil a Г©tГ© approuvГ© uniquement pour le traitement de l'apnГ©e du sommeil. Le modafinil peut provoquer une somnolence chez certains patients. Modiodal Generique Le modafinil a Г©tГ© dГ©veloppГ© Г l'origine pour traiter la somnolence due au dГ©calage horaire et au travail postГ© chez les personnes travaillant en rotation. La dose peut varier considГ©rablement en fonction de ce pour quoi le patient est prescrit. Modafinil a un certain potentiel d'abus. Le modafinil agit en augmentant l'activitГ© de la dopamine dans le cerveau et entraГ®ne une augmentation de la vigilance et de l'Г©veil. Pour cette raison, le modafinil a une demi-vie assez longue et est donc actif pendant une longue pГ©riode dans le corps. Le modafinil peut interfГ©rer avec la fonction normale de la vessie ou des intestins. L'utilisation de Modafinil aide Г l'induction et au maintien du sommeil. C'est un dГ©rivГ© de l'indole. Ce mГ©dicament ne doit pas ГЄtre pris par les personnes souffrant de maladies cardiovasculaires, de problГЁmes hГ©patiques, de problГЁmes rГ©naux, de troubles Г©pileptiques, d'antГ©cГ©dents de dГ©pression ou d'apnГ©e du sommeil sГ©vГЁre, car ces conditions peuvent ГЄtre aggravГ©es par le mГ©dicament. Il est utilisГ© tel quel dans les essais cliniques. Le modafinil est parfois utilisГ© pour traiter les troubles du sommeil liГ©s au travail postГ©. Les propriГ©tГ©s antidГ©pressives ont Г©tГ© attribuГ©es Г la liaison de la sГ©rotonine aux rГ©cepteurs, entraГ®nant une diminution de l'activation du systГЁme sГ©rotoninergique. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es.
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Le modafinil augmente le flux sanguin et on pense également qu'il traverse la barrière hémato-encéphalique. Dans l'étude, neuf travailleurs postés souffrant de troubles du sommeil liés au travail posté ont reçu du Modafinil pendant quatre semaines. Le modafinil est un médicament qui peut aider les gens à rester éveillés. Jusqu'à présent, le modafinil est l'un des deux médicaments qui a fait l'objet du plus grand nombre d'études de recherche. Le modafinil doit être pris avec de la nourriture. En raison de la longue demi-vie du modafinil de 12,3 heures, le modafinil met plus de temps à libérer la dopamine dans le cerveau que les autres stimulants à courte durée d'action. Modiodal Generique Lors de la prise de modafinil, les patients doivent éviter les boissons contenant de l'alcool ou d'autres dépresseurs du SNC tels que la marijuana, les sédatifs ou les hypnotiques, car ceux-ci peuvent aggraver l'effet. Ceci provoque une accumulation de la substance active, dont la durée d'efficacité est en fait dose-dépendante. La forme posologique en comprimé est disponible en dosages de 200 mg, 400 mg et 800 mg. Par conséquent, les schémas de prescription du modafinil doivent être étroitement surveillés par ceux qui travaillent dans le domaine de la santé. Il n'est disponible que sous forme de pilules rondes non marquées et il n'est pas possible de distinguer une dose d'une autre. Plusieurs études préliminaires ont indiqué que le modafinil peut affecter les concentrations de dopamine et de noradrénaline dans le cerveau. Le modafinil a également été administré à un certain nombre d'autres patients qui n'ont pas été testés pour la démence. Il est pris trois fois par jour, à au moins 1 heure d'intervalle. Modafinil est également connu sous le nom commercial Armodafinil ou R-modafinil. On pense que le modafinil augmente les niveaux de dopamine en bloquant le transporteur de la dopamine.
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Alors que les amphГ©tamines sont des stimulants, les cyclopyrrolones sont des dГ©presseurs du SNC (contrairement aux barbituriques par exemple). Le modafinil est un stimulant synthГ©tique qui augmente l'activitГ© de certains systГЁmes de neurotransmetteurs. Il est plus efficace lorsqu'il est pris avant de dormir et donne les meilleurs rГ©sultats s'il est pris le matin ou en milieu d'aprГЁs-midi. il n'augmente pas le sentiment de vigilance. AprГЁs cet incident, le docteur Jouvet a commencГ© Г expГ©rimenter avec des animaux et a conclu qu'il pouvait amГ©liorer le mГ©tabolisme du cerveau grГўce Г l'injection de dioxyde de carbone. Une dose de 150 mg Г©quivaut Г 200 mg d'armodafinil (Nuvigil, Г©galement commercialisГ© par Sun Pharmaceuticals). Il est important que le patient utilise le mГЄme dispositif d'injection de drogue Г chaque fois. Modiodal Generique Il est trГЁs important qu'avant de commencer Г utiliser Modafinil Pilules que vous informiez votre mГ©decin de toute condition mГ©dicale dont vous souffrez. Cependant, il peut ГЄtre plus difficile pour l'utilisateur de rГ©duire le temps passГ© Г dormir aprГЁs avoir utilisГ© Modafinil, si son rythme de sommeil rГ©gulier est interrompu ou s'il est pris pour compenser un cycle de sommeil insuffisant ou perturbГ©. Le modafinil semble ГЄtre sГ©lectif pour une sous-population de cellules du thalamus et de l'hypothalamus, inhibant les cellules les plus sensibles au stress. Le modafinil est un composГ© racГ©mique, et seul l'Г©nantiomГЁre (+) est actif. Donc, vous pouvez demander, le modafinil fonctionne-t-il ? Cette rГ©ponse est difficile Г dire, mais cela ne signifie pas que cela ne fonctionnera pas. L'adГ©nosine est responsable de la rГ©gulation des cycles veille/sommeil dans le cerveau, et lorsqu'elle est libГ©rГ©e pendant le sommeil, elle aide Г garder les gens Г©veillГ©s. La dose habituelle recommandГ©e est de 100 Г 200 mg par voie orale le matin Г jeun. Le modafinil peut ГЄtre plus efficace que le placebo pour les dГ©ficiences associГ©es Г l'apnГ©e du sommeil, et les personnes sans narcolepsie peuvent avoir moins d'insomnie qu'avec le placebo, mais les preuves sont mitigГ©es. Le fonctionnement exact du mГ©dicament n'a pas encore Г©tГ© prouvГ©, cependant, il est connu pour stimuler les parties du cerveau responsables de la production de neurotransmetteurs et ainsi augmenter l'Г©veil. Sa biodisponibilitГ© est d'environ 50 %. Les deux Г©nantiomГЁres sont des isomГЁres optiques et deux diastГ©rГ©oisomГЁres sont gГ©nГ©ralement produits. Comme l'amphГ©tamine, le modafinil agit Г©galement sur le transporteur de la dopamine dans le cerveau, augmentant la disponibilitГ© de la dopamine au niveau de ses rГ©cepteurs. Son activitГ© biologique est similaire Г celle des stimulants du SNC apparentГ©s, l'amphГ©tamine et le mГ©thylphГ©nidate, et est gГ©nГ©ralement considГ©rГ©e comme moins puissante que ces deux composГ©s.
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