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Le modafinil n'est pas approuvГ© pour le traitement de la fatigue associГ©e Г  des conditions mГ©dicales chroniques. Il est Г©tudiГ© pour les troubles cardiovasculaires tels que l'insuffisance cardiaque chronique et l'hypertension secondaire. Certaines Г©tudes ont montrГ© qu'une certaine quantitГ© d'exposition Г  la lumiГЁre de faible intensitГ© peut ГЄtre utilisГ©e comme stratГ©gie non pharmacologique pour aider Г  rГ©duire la somnolence, en particulier dans le travail postГ© et le dГ©calage horaire, oГ№ la luminothГ©rapie Г  haute intensitГ© s'est avГ©rГ©e efficace. Il a Г©galement Г©tГ© constatГ© qu'il augmentait les niveaux d'acГ©tylcholine et de sГ©rotonine dans le cortex prГ©frontal. Le modafinil a Г©tГ© utilisГ© chez des personnes atteintes de sclГ©rose en plaques, et il existe des rapports de cas sur son utilisation dans la schizophrГ©nie. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. Le modafinil doit ГЄtre pris au moins quatre heures avant de dormir, et une nuit complГЁte de sommeil est recommandГ©e. Modafinil Europe Le modafinil peut diminuer l'exposition Г  l'antihistaminique diphenhydramine, son utilisation n'est donc pas recommandГ©e. Aux Г‰tats-Unis, le modafinil est approuvГ© pour une utilisation chez les adultes souffrant de somnolence causГ©e par la narcolepsie. La concentration exacte d'ingrГ©dients actifs dans le modafinil n'est pas publique, mais elle peut ГЄtre d'environ 300 mg pour 100 mg de modafinil. Les personnes atteintes de narcolepsie prГ©sentent souvent de multiples symptГґmes. Le modafinil est capable d'affecter le systГЁme GABAergique du cerveau, qui stimule la voie de l'Г©veil. Modafinil Vente Libre Ces deux derniГЁres rГ©gions du cerveau sont importantes pour la rГ©gulation du sommeil. Le modafinil empГЄche l'adГ©nosine de se lier aux rГ©cepteurs cellulaires du cerveau, l'empГЄchant ainsi de se dГ©grader. Certaines de ces rГ©actions peuvent ГЄtre dose-dГ©pendantes et prГ©visibles. La solution de modafinil se prГ©sente sous la forme de solutions de 100 milligrammes et 200 milligrammes qui semblent claires et incolores. La dose maximale recommandГ©e est de 400 mg par jour, Г  prendre avec le petit-dГ©jeuner. Le modafinil agit dans le cerveau en augmentant directement ou indirectement les niveaux de dopamine dans le cerveau. Il a Г©tГ© dГ©montrГ© qu'il amГ©liore l'apprentissage et la mГ©moire chez les rats et peut avoir des avantages dans le traitement de l'hypoglycГ©mie, du trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH) et du trouble dГ©pressif majeur.

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